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Table 2 Comparison of characteristics between patients with response and those without response

From: Apparent diffusion coefficient for the prediction of tumor response to neoadjuvant chemo-radiotherapy in locally advanced rectal cancer

Parameter

OR

95% CI

P value

Univariate analysis

 Age (years)

1.015

0.976–1.057

0.451

 Male sex

1.284

0.512–3.217

0.594

 Clinical tumor depth

  T2

1

0.814

  T3

3

0.084–107.447

0.547

  T4

1.576

0.095–26.067

0.751

 Clinical lymph node metastases

  N0

1

0.189

  N1

2.160

0.756–6.173

0.151

  N2

2.850

0.878–9.252

0.081

 Histological classification

  High differentiation

1

0.310

  Moderate differentiation

3.600

0.280–46.359

0.326

  Low differentiation

5.444

0.540–54.927

0.151

 Pre-ADC

11.818

4.328–32.272

< 0.001

 Post-ADC

2.312

0.974–5.492

0.058

 ΔADC%

9.225

3.441–24.728

< 0.001

Multivariable analysis

 Clinical Lymph node metastases

  N0

1

0.129

  N1

6.226

0.253–153.237

0.263

  N2

15.486

0.871–275.198

0.062

 Pre-ADC

5.521

1.344–22.673

0.018

 Post-ADC

2.108

0.433–10.259

0.355

 ΔADC%

9.886

2.460–39.720

0.001