Risk factors for osteoradionecrosis of the jaw in patients with head and neck squamous cell carcinoma

Radiation Oncology

Table 2 Comparison of the dose–volume histograms

Characteristic		V10 (%)	V20 (%)	V30 (%)	V40 (%)	V50 (%)	V60 (%)	V70 (%)
ORNJ
No	Median	92.90	86.59	76.61	65.07	41.68	12.16	0.03
Yes	Median	93.99	90.29	84.16	73.48	61.37	35.31	3.22
	p value*	0.4050	0.2340	0.0148	0.0016	< 0.0001	< 0.0001	0.0041
RT technique
3D-CRT	Median	87.57	81.37	76.07	70.47	52.84	26.62	0.21
IMRT	Median	99.42	92.92	79.39	53.95	27.30	5.33	0.00
	p value*	< 0.0001	< 0.0001	0.6300	< 0.0001	< 0.0001	< 0.0001	0.0001
Primary tumor site
OPC/OC	Median	95.04	90.24	83.21	73.87	56.26	32.03	0.00
Others	Median	88.99	82.00	69.43	57.59	32.86	3.98	1.19
	p value*	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001

^*Mann–Whitney U test
V10, V20, V30, V40, V50, V60, and V70, represent relative volumes of the jaw exposed to 10, 20, 30, 40, 50, 60, and 70 Gy, respectively
ORNJ, osteoradionecrosis of the jaw; RT, radiation therapy; 3D-CRT, 3-dimensional conformal radiation therapy; IMRT, intensity-modulated radiation therapy; OPC, oropharyngeal cancer; OC, oral cancer

ISSN: 1748-717X