Skip to main content
Fig. 5 | Radiation Oncology

Fig. 5

From: Overexpression of HOTAIR leads to radioresistance of human cervical cancer via promoting HIF-1α expression

Fig. 5

Effect of HIF-1α knockdown on the cell viability and apoptosis of HeLa and C33A cell exposed to radiation. HeLa and C33A cells were divided into six groups: control, radiation, radiation+Ad-GFP, radiation+Ad-HOTAIR, radiation+Ad-HOTAIR + si-NC, and radiation+Ad-HOTAIR + si-HIF-1α groups. The cell viability (a) and apoptosis (b) of HeLa and C33A cell exposed to radiation were examined. The data are represented as mean ± SD. **vs control cells, P < 0.01; ##vs cells irradiated with a dose of 2 Gy and transfected with Ad-GFP, P < 0.01; &vs cells irradiated with a dose of 2 Gy and transfected with Ad-HOTAIR and si-NC (scrambled sequence), P < 0.01. All the experiment performed in triplicate

Back to article page

Radiation Oncology

ISSN: 1748-717X

Contact us